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# Skincare Glossary

Every skincare and dermatology term you need to know, explained in plain English.

[A](#letter-A)[B](#letter-B)[C](#letter-C)[D](#letter-D)[E](#letter-E)[F](#letter-F)[G](#letter-G)[H](#letter-H)[I](#letter-I)[J](#letter-J)[K](#letter-K)[L](#letter-L)[M](#letter-M)[N](#letter-N)[O](#letter-O)[P](#letter-P)Q[R](#letter-R)[S](#letter-S)[T](#letter-T)[U](#letter-U)[V](#letter-V)[W](#letter-W)[X](#letter-X)Y[Z](#letter-Z)

[Home](/)/ Glossary 

## A

[AHA (Alpha Hydroxy Acid)](/glossary/aha-alpha-hydroxy-acid) — Alpha hydroxy acids are a group of water-soluble acids derived from fruits, milk, and sugar cane. The most common AHAs i… 

[Antioxidant](/glossary/antioxidant) — Antioxidants are molecules that protect the skin from damage caused by free radicals — unstable atoms generated by UV ra… 

[Astringent](/glossary/astringent) — An astringent is a topical product or ingredient that causes the contraction of skin cells and tissues, temporarily tigh… 

[Atopic Dermatitis](/glossary/atopic-dermatitis) — Atopic dermatitis is a chronic, inflammatory skin condition and the most common form of eczema. It causes dry, itchy, re… 

## B

[Barrier Function](/glossary/barrier-function) — The skin's barrier function refers to the protective role of the outermost layer of the epidermis, the stratum corneum. … 

[BHA (Beta Hydroxy Acid)](/glossary/bha-beta-hydroxy-acid) — Beta hydroxy acid refers primarily to salicylic acid, an oil-soluble exfoliant that penetrates into pores to dissolve ex… 

[Broad Spectrum](/glossary/broad-spectrum) — Broad spectrum is a sunscreen classification indicating that a product protects against both UVA and UVB rays. UVB rays … 

## C

[Ceramides](/glossary/ceramides) — Ceramides are a family of waxy lipid molecules that occur naturally in the skin and make up about 50% of the lipids in t… 

[Chemical Exfoliant](/glossary/chemical-exfoliant) — A chemical exfoliant is a skincare product that uses acids or enzymes to dissolve the bonds between dead skin cells, pro… 

[Collagen](/glossary/collagen) — Collagen is the most abundant protein in the human body, providing structural support to the skin, bones, tendons, and l… 

[Comedogenic](/glossary/comedogenic) — Comedogenic describes an ingredient or product that has a tendency to clog pores and contribute to the formation of come… 

[Comedone](/glossary/comedone) — A comedone is a basic acne lesion formed when a hair follicle becomes clogged with dead skin cells, sebum, and sometimes… 

[Contact Dermatitis](/glossary/contact-dermatitis) — Contact dermatitis is a localized skin inflammation that occurs when the skin comes into direct contact with a substance… 

[Cystic Acne](/glossary/cystic-acne) — Cystic acne is the most severe form of acne, characterized by large, deep, painful, inflamed breakouts that form beneath… 

## D

[Dermatitis](/glossary/dermatitis) — Dermatitis is a general term for skin inflammation, characterized by redness, swelling, itching, and sometimes blisterin… 

[Dermis](/glossary/dermis) — The dermis is the thick middle layer of the skin, located between the epidermis (outer layer) and the hypodermis (subcut… 

[Desquamation](/glossary/desquamation) — Desquamation is the natural, ongoing process by which the outermost layer of dead skin cells (corneocytes) sheds from th… 

[Double Cleansing](/glossary/double-cleansing) — Double cleansing is a two-step face washing method that originated in Korean and Japanese skincare routines. The first s… 

## E

[Elastin](/glossary/elastin) — Elastin is a highly elastic protein found in the dermis that allows the skin to stretch and snap back to its original sh… 

[Emollient](/glossary/emollient) — An emollient is a type of moisturizing ingredient or product that works by filling in the gaps between skin cells with l… 

[Emulsifier](/glossary/emulsifier) — An emulsifier is an ingredient that allows two normally immiscible substances — typically oil and water — to mix togethe… 

[Enzymes](/glossary/enzymes) — In skincare, enzymes are biological proteins used as gentle exfoliating agents. They work by breaking down the keratin p… 

[Epidermis](/glossary/epidermis) — The epidermis is the outermost layer of the skin and serves as the body's primary physical barrier against the environme… 

[Exfoliation](/glossary/exfoliation) — Exfoliation is the process of removing dead skin cells from the surface of the skin to reveal fresher, smoother skin ben… 

## F

[Fibroblast](/glossary/fibroblast) — Fibroblasts are the primary cells in the dermis responsible for producing collagen, elastin, glycosaminoglycans (like hy… 

[Fitzpatrick Scale](/glossary/fitzpatrick-scale) — The Fitzpatrick Scale is a numerical classification system developed by dermatologist Thomas Fitzpatrick in 1975 that ca… 

[Free Radicals](/glossary/free-radicals) — Free radicals are unstable, reactive molecules with unpaired electrons that damage cells by stealing electrons from othe… 

## G

[Glycerin](/glossary/glycerin) — Glycerin (also called glycerol) is one of the most effective and widely used humectant ingredients in skincare. It is a … 

[Glycolic Acid](/glossary/glycolic-acid) — Glycolic acid is the smallest and most widely researched alpha hydroxy acid (AHA), derived from sugar cane. Its small mo… 

## H

[Humectant](/glossary/humectant) — A humectant is a type of moisturizing ingredient that attracts and binds water molecules from the environment and from d… 

[Hyaluronic Acid](/glossary/hyaluronic-acid) — Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found throughout the body's connective tissues, with the… 

[Hyperpigmentation](/glossary/hyperpigmentation) — Hyperpigmentation is a common skin condition where patches of skin become darker than the surrounding areas due to exces… 

[Hypodermis](/glossary/hypodermis) — The hypodermis, also called the subcutaneous layer or subcutis, is the deepest layer of the skin lying below the dermis.… 

## I

[Inflammation](/glossary/inflammation) — Inflammation is the immune system's response to injury, infection, or irritation, characterized by redness, swelling, he… 

[Irritant](/glossary/irritant) — An irritant is any substance that causes a non-allergic inflammatory reaction when it comes into contact with the skin. … 

## J

[Jojoba Oil](/glossary/jojoba-oil) — Jojoba oil is a liquid wax ester extracted from the seeds of the jojoba plant (Simmondsia chinensis), native to the sout… 

## K

[Keratin](/glossary/keratin) — Keratin is a tough, fibrous structural protein that is the primary component of the outermost layer of skin (stratum cor… 

[Keratinocyte](/glossary/keratinocyte) — Keratinocytes are the predominant cell type in the epidermis, making up approximately 90% of epidermal cells. They are p… 

## L

[Lactic Acid](/glossary/lactic-acid) — Lactic acid is an alpha hydroxy acid (AHA) derived from milk that serves as a gentle chemical exfoliant. It has a larger… 

[LED (Light Emitting Diode)](/glossary/led-light-emitting-diode) — In skincare, LED refers to light emitting diode technology used to deliver specific wavelengths of light to the skin. Di… 

[Lipid Barrier](/glossary/lipid-barrier) — The lipid barrier (also called the lipid matrix or lipid bilayer) is the intercellular 'mortar' between the corneocytes … 

## M

[Melanin](/glossary/melanin) — Melanin is the natural pigment produced by melanocytes in the basal layer of the epidermis that gives skin, hair, and ey… 

[Melanocyte](/glossary/melanocyte) — Melanocytes are specialized cells located in the basal layer of the epidermis that produce melanin, the pigment responsi… 

[Microbiome](/glossary/microbiome) — The skin microbiome refers to the vast community of microorganisms — including bacteria, fungi, viruses, and mites — tha… 

[Milia](/glossary/milia) — Milia are small, white or yellowish, dome-shaped bumps that appear on the skin when keratin (a protein) becomes trapped … 

[Moisturizer](/glossary/moisturizer) — A moisturizer is a skincare product designed to hydrate the skin and prevent water loss by combining three types of mois… 

## N

[Niacinamide](/glossary/niacinamide) — Niacinamide (also known as nicotinamide) is a form of vitamin B3 that has become one of the most versatile and popular a… 

[Non-Comedogenic](/glossary/non-comedogenic) — Non-comedogenic is a term used to describe skincare and cosmetic products that are formulated to be less likely to clog … 

## O

[Occlusives](/glossary/occlusives) — Occlusives are a category of moisturizing ingredients that work by forming a physical barrier on the skin's surface to p… 

[Oxidative Stress](/glossary/oxidative-stress) — Oxidative stress occurs when there is an imbalance between the production of free radicals (reactive oxygen species) and… 

## P

[Peptides](/glossary/peptides) — Peptides are short chains of amino acids (typically 2-50 amino acids long) that serve as building blocks for proteins li… 

[pH Balance](/glossary/ph-balance) — pH (potential of hydrogen) is a measure of acidity or alkalinity on a scale of 0 to 14, with 7 being neutral. Healthy sk… 

[Photobiomodulation](/glossary/photobiomodulation) — Photobiomodulation is the use of specific wavelengths of light — typically red and near-infrared — to stimulate cellular… 

[PIE (Post-Inflammatory Erythema)](/glossary/pie-post-inflammatory-erythema) — Post-inflammatory erythema (PIE) refers to the flat, pink to red or purple marks left on the skin after an inflammatory … 

[PIH (Post-Inflammatory Hyperpigmentation)](/glossary/pih-post-inflammatory-hyperpigmentation) — Post-inflammatory hyperpigmentation (PIH) is a type of hyperpigmentation that occurs as the skin heals from inflammation… 

[Pore](/glossary/pore) — Pores are the tiny openings on the skin's surface through which hair follicles reach the surface and through which sebum… 

[Propolis](/glossary/propolis) — Propolis is a natural, resinous substance produced by honeybees from tree buds, sap flows, and other botanical sources. … 

## R

[Red Light Therapy](/glossary/red-light-therapy) — Red light therapy uses wavelengths between 620-700 nanometers to penetrate the skin and stimulate mitochondrial energy p… 

[Retinoid](/glossary/retinoid) — Retinoids are a class of chemical compounds derived from vitamin A that are widely considered the gold standard in anti-… 

[Retinol](/glossary/retinol) — Retinol is the most popular and widely available over-the-counter form of vitamin A (retinoid) used in skincare. It is a… 

[Rosacea](/glossary/rosacea) — Rosacea is a chronic, inflammatory skin condition that primarily affects the central face — cheeks, nose, chin, and fore… 

## S

[Salicylic Acid](/glossary/salicylic-acid) — Salicylic acid is a beta hydroxy acid (BHA) derived from willow bark that is one of the most effective and widely used i… 

[Sebaceous Gland](/glossary/sebaceous-gland) — Sebaceous glands are small, oil-producing glands attached to hair follicles throughout the body (except on the palms and… 

[Sebum](/glossary/sebum) — Sebum is the waxy, oily substance produced by sebaceous glands to lubricate and waterproof the skin and hair. It is comp… 

[Sensitized Skin](/glossary/sensitized-skin) — Sensitized skin is a condition where the skin has become temporarily reactive, irritated, and easily aggravated due to e… 

[Skin Cycling](/glossary/skin-cycling) — Skin cycling is a skincare method popularized by dermatologist Dr. Whitney Bowe that involves rotating active ingredient… 

[SPF](/glossary/spf) — SPF stands for Sun Protection Factor, a numerical rating that indicates how much longer a sunscreen allows you to stay i… 

[Stratum Corneum](/glossary/stratum-corneum) — The stratum corneum is the outermost sublayer of the epidermis and the body's first physical barrier against the externa… 

[Sunscreen](/glossary/sunscreen) — Sunscreen is a topical product that protects the skin from the harmful effects of ultraviolet (UV) radiation, which caus… 

## T

[Toner](/glossary/toner) — A toner is a liquid skincare product applied after cleansing and before serums and moisturizers. Historically, toners we… 

[Transepidermal Water Loss (TEWL)](/glossary/transepidermal-water-loss-tewl) — Transepidermal water loss (TEWL) is the process by which water passes from the dermis through the epidermis and evaporat… 

[Tretinoin](/glossary/tretinoin) — Tretinoin (all-trans retinoic acid) is the most potent and well-researched prescription retinoid, available under brand … 

## U

[Urea](/glossary/urea) — Urea is a naturally occurring compound found in the skin as part of the natural moisturizing factor (NMF) — the collecti… 

[UVA](/glossary/uva) — UVA (Ultraviolet A) rays are the longest wavelength of ultraviolet radiation (320-400 nm) emitted by the sun. They accou… 

[UVB](/glossary/uvb) — UVB (Ultraviolet B) rays are medium-wavelength ultraviolet radiation (280-320 nm) that primarily affects the epidermis, … 

## V

[Vitamin C (Ascorbic Acid)](/glossary/vitamin-c-ascorbic-acid) — Vitamin C (L-ascorbic acid) is one of the most researched and effective antioxidant ingredients in skincare. It neutrali… 

[Vitamin E (Tocopherol)](/glossary/vitamin-e-tocopherol) — Vitamin E (tocopherol) is a fat-soluble antioxidant that occurs naturally in the skin's sebum and plays a critical role … 

## W

[Whiteheads](/glossary/whiteheads) — Whiteheads (closed comedones) are a type of non-inflammatory acne that appears as small, flesh-colored or white bumps on… 

[Witch Hazel](/glossary/witch-hazel) — Witch hazel is a plant-derived ingredient extracted from the bark and leaves of the Hamamelis virginiana shrub, native t… 

## X

[Xeroderma](/glossary/xeroderma) — Xeroderma is the medical term for abnormally dry skin, characterized by roughness, tightness, flaking, scaling, cracking… 

## Z

[Zinc (topical)](/glossary/zinc-topical) — Topical zinc refers to various zinc compounds used in skincare for their anti-inflammatory, antimicrobial, wound-healing… 

[Zinc Oxide](/glossary/zinc-oxide) — Zinc oxide is a mineral (inorganic) sunscreen ingredient that provides broad-spectrum protection against both UVA and UV… 

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